The Laboratory for Molecular Medicine (LMM) at Partners HealthCare Personalized Medicine is seeking a motivated individual to work in a cutting-edge environment to serve as a variant scientist on our Genomic Curation Team. The LMM is a leading molecular diagnostic laboratory that supports clinicians and researchers at Massachusetts General Hospital and Brigham and Women’s Hospital, as well as serving as a reference laboratory for national and international institutions. The LMM also functions as a clinical laboratory and genomic interpretation center for translational research grants.
The Genomic Curation Team is responsible for maintaining excellence and innovation for our clinical testing operations and translational research grants, including panel-based testing, exome sequencing, and genome sequencing. Team members provide thorough review of all data on variants identified during the testing process, using detailed evidenced-based rules for variant classification. The team also performs gene assessment to evaluate the evidence and validity of gene-disease associations. This position would also help to innovate and scale the curation efforts within the laboratory.
The Variant Scientist position will interact with geneticists, genetic counselors, fellows within the ABMGG and MGP fellowship programs, bioinformaticians, and other laboratory and clinical staff. Opportunities to publish manuscripts with LMM staff and/or external investigators may also be a possibility.
Qualified individuals should have a Ph.D. in genetics, biology or related field or a MA/MS in genetic counseling, genetics, or molecular biology. Experience with variant/gene classification, including familiarity with the ACMG/AMP Standards and Guidelines for the Interpretation of Sequence Variants, is preferred.
Internal Number: 001122
About Partners HealthCare Personalized Medicine Laboratory for Molecular Medicine
Partners HealthCare Personalized Medicine is a part of Partners HealthCare System. Partners HealthCare, founded by Brigham and Women’s Hospital (BWH) and Massachusetts General Hospital (MGH), is one of the largest health care systems in the United States. The system is world-renowned for its contributions to the advancement of health care through patient care, research, teaching the next generation of physicians, and service to the community. The Partners HealthCare System comprises more than 10 acute care and specialty hospitals, a physicians network, home care, a managed care organization and many research facilities. We serve the health needs of the local community as well as those of patients from throughout the country and the world.The mission of Partners Personalized Medicine is to utilize genetics and genomics to improve the care of patients through the promotion and implementation of personalized medicine in caring for patients throughout the Partners HealthCare System and in healthcare nationally and globally.